Western blot
0.2-1 ug/ml| Product Name | PPARD antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-PPARD antibody: synthetic peptide directed towards the n terminal of human PPARD |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Bovine,Dog,Guinea Pig,Horse,Human,Mouse,Pig,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PPARD |
|---|---|
| Gene Synonyms | FAAR MGC3931 NR1C2 NUC1 NUCI NUCII PPAR-beta PPARB |
| Gene Full Name | Peroxisome proliferator-activated receptor delta |
| Gene Summary | PPARD is a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR delta and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. |
| Alternative Names | FAAR MGC3931 NR1C2 NUC1 NUCI NUCII PPAR-beta PPARB |
| Molecular Weight(MW) | 49kDa |
| Sequence | 441 amino acids |
| Entrez Gene | 5467 |
|---|---|
| Protein Accession | NP_001034783 |
Western blot
0.2-1 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM108901