Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Small Intestine| Product Name | Rabbit anti-MRGPRX1 Antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GPCR, MRGX1, SNSR4 |
| Immunogen | The immunogen for Anti-MRGPRX1 antibody is: synthetic peptide directed towards the C-terminal region of Human MRGPRX1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MRGPRX1 |
|---|---|
| Gene Synonyms | GPCR MRGX1 SNSR4 |
| Gene Full Name | MAS-related GPR, member X1 |
| Gene Summary | MRGPRX1 is an orphan receptor. MRGPRX1 is probably involved in the function of nociceptive neurons. It may regulate nociceptor function and/or development, including the sensation or modulation of pain. MRGPRX1 is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. MRGPRX1 is activated by the antimalarial drug, chloroquine and may mediate chloroquine-induced itch, in an histamine-independent manner. |
| Alternative Names | GPCR MRGX1 SNSR4 |
| Molecular Weight(MW) | 36kDa |
| Sequence | 322 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Small Intestine| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM118257