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Rabbit anti-PDCD8 polyclonal antibody - N-terminal region
Catalog Number:OM121818
OM121818
Discount Price
OM121818-100ul
1~2 Week
100ul
OM121818-50ul
50ul
OM121818-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-PDCD8 polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias RP3-438D16.2, AIF, MGC111425, PDCD8, COXPD6
Immunogen The immunogen for anti-PDCD8 antibody: synthetic peptide directed towards the N terminal of human PDCD8
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogHumanSheep
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol PDCD8
Gene Synonyms RP3-438D16.2
AIF
MGC111425
PDCD8
COXPD6
Gene Full Name Apoptosis-inducing factor, mitochondrion-associated, 1
Gene Summary AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Alternative Names RP3-438D16.2
AIF
MGC111425
PDCD8
COXPD6
Molecular Weight(MW) 66kDa
Sequence 609 amino acids
Database Links
Entrez Gene 9131
SwissProt ID O95831-3
Protein Accession NP_665811
Application Notes WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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