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PDCD8 Antibody
Catalog Number:OM287652
OM287652
Discount Price
OM287652-100ul
1~2 Week
100ul
OM287652-50ul
50ul
OM287652-20ul
20ul
1~2 Week
Product Profile
Product Name PDCD8 Antibody
Antibody Type Primary Antibodies
Antigen Alias PDCD8, AIF, CMT2D, CMTX4, COWCK, NADMR, NAMSD, PDCD8, COXPD6
Product description AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.1) Delettre, C., (er) J. Biol. Chem. (2006) In press.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PDCD8.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
PDCD8 antibody can be used for detection of PDCD8 by ELISA at 1:62500. PDCD8 antibody can be used for detection of PDCD8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity DogHumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol AIFM1
Alternative Names PDCD8
AIF
CMT2D
CMTX4
COWCK
NADMR
NAMSD
PDCD8
COXPD6
Molecular Weight(MW) 36 kDa, 67 kDa, 66 kDa
Database Links
Entrez Gene 9131
Protein Accession NP_665812
Application

Application

Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
Positive Control 1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes PDCD8 antibody can be used for detection of PDCD8 by ELISA at 1:62500. PDCD8 antibody can be used for detection of PDCD8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store PDCD8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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