All products Antibodies Anti-c-MYC antibody

Anti-c-MYC antibody

Catalog Number：OM641731

  • Western blot analysis using c-MYC antibody against A431 (1), Hep G2 (2) cell lysate.

  • Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using c-MYC antibody with DAB staining

Product Profile

Product Name Anti-c-MYC antibody
Antibody Type Primary Antibodies
Immunogen 
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
Species Reactivity

HumanMouseRat
Concentration 1 mg/ml
Purification Protein A

Target Information

Gene Symbol MYC
Gene Synonyms
MRTL
MYCC
c-Myc
bHLHe39
Gene Full Name MYC proto-oncogene, bHLH transcription factor
Gene Summary
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Molecular Weight(MW) 49 kDa
Source Rabbit
Cellular Localization Nucleus

Application

  • WB

    Western blot analysis using c-MYC antibody against A431 (1), Hep G2 (2) cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using c-MYC antibody with DAB staining

Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azi.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM641731
  • Price: $336.00
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  • Lead time: 4~6 Week

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