All products Antibodies CREB-1 Antibody (240) PE

CREB-1 Antibody (240) PE

Catalog Number：OM155192

  • Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and cytoplasmic localization.

  • Western blot analysis of CREB-1 expression in A-431 nuclear extract.

  • Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Antibodies tested include CREB-1 (24H4B): (A) and CREB-1 (240): (B).

  • Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal rabbit IgG: .

Product Profile

Product Name CREB-1 Antibody (240) PE
Antibody Type Primary Antibodies
Modification Notes Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis-acting promoter and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The ATF/CREB family includes CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. This family of proteins contains highly divergent N-terminal domains, but shares a C-terminal leucine zipper for dimerization and DNA binding. Although CREB can bind to DNA in an unphosphorylated state, it cannot activate transcription. Phosphorylation of CREB on Ser 133 by protein kinase A facilitates its interaction with the CREB-binding protein (CBP) and activates the basal transcription complex. CREB functions in neoglucogenesis through interactions with the nuclear coactivator PGC-1. CREB may play a role in the pathogenesis of type II diabetes and dilated cardiomyopathy.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIPIFFCELISA
recommended for detection of CREB-1A of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; non cross-reactive with CREB-1B:
Species Reactivity

HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified

Target Information

Alternative Names
epitope mapping within the &alpha
region of CREB-1 of human origin
Tissue Specificity epitope mapping within the α region of CREB-1 of human origin

Database Links

Entrez Gene 1385

Application

  • Application

    Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and cytoplasmic localization.

  • Application

    Western blot analysis of CREB-1 expression in A-431 nuclear extract.

  • Application

    Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Application

    Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal rabbit IgG: .

  • Application

    Antibodies tested include CREB-1 (24H4B): (A) and CREB-1 (240): (B).

  • Application

    Intracellular FCM analysis of fixed and permeabilized Jurkat cells. Black line histogram represents the isotype control, normal rabbit IgG: .

Application Notes
recommended for detection of CREB-1A of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; non cross-reactive with CREB-1B:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

Submit an review for OM155192
Submit an review for OM155192
  • Catalog Number: OM155192
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: Out of stock
  • Lead time: 4~6 Week

  • Quantity:
    - +
  • Shipping to (Please select)
Add to cart
Add to Wishlist
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.
PRODUCT CATEGORIES
Primary antibodies Secondary antibodies Tags antibodies Flow cytometry antibodies
SUPPORT
Catalogs Newsletter Order Online Buying FAQs Distributor
COMPANY
Profile Strategy Careers
CONTACT
Contact us

2013 © Omnimabs , All Rights Reserved.