All products Antibodies Cox-2 Antibody (H-62)

Cox-2 Antibody (H-62)

Catalog Number:OM159932

  • Immunoperoxidase staining of formalin fixed, paraffin-embedded human urinary bladder tissue showing cytoplasmic and nuclear staining of urothelial cells.

  • Western blot analysis of Cox-2 expression in PMA + LPS-induced RAW 264.7 whole cell lysate.

Product Profile

Product Name Cox-2 Antibody (H-62)
Antibody Type Primary Antibodies
Modification Notes Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general “housekeeping” functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs .

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIPIFFCELISA

recommended for detection of Cox-2 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Alternative Names
epitope corresponding to amino acids 50-111 of Cox-2 of human origin
Tissue Specificity epitope corresponding to amino acids 50-111 of Cox-2 of human origin

Database Links

Entrez Gene 5743

Application

  • Application

    Immunoperoxidase staining of formalin fixed, paraffin-embedded human urinary bladder tissue showing cytoplasmic and nuclear staining of urothelial cells.

  • Application

    Western blot analysis of Cox-2 expression in PMA + LPS-induced RAW 264.7 whole cell lysate.

Application Notes
recommended for detection of Cox-2 of mouse, rat and human origin by WB, IP, IF, FCM and ELISA; also reactive with additional species, including equine, canine, bovine and porcine:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM159932
  • Price: $336.00
  • Discount Price
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  • Store: Out of stock
  • Lead time: 4~6 Week
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