All products Antibodies IKK-γ (phospho Ser376) Antibody

IKK-γ (phospho Ser376) Antibody

Catalog Number：OM281801

  • Immunohistochemical analysis of paraffin-embedded human brain tissue using IKK-γ (Phospho-Ser376) antibody (left) or the same antibody preincubated with blocking peptide (right).

Product Profile

Product Name IKK-γ (phospho Ser376) Antibody
Antibody Type Primary Antibodies
Product description 
Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males. In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation.1) Li Y., Proc. Natl. Acad. Sci. U.S.A. 96:1042-1047(1999).
Immunogen 
IKK-γ (phospho Ser376) antibody was raised against a peptide sequence around phosphorylation site of Serine 376 (Y-L-S (p)-S-P) derived from Human IKK-γ.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

Human
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol IKBKG
Alternative Names
FIP3
IKBKG
IKKAP1
IKKG
NF-kappaB
Molecular Weight(MW) 48 kDa
Tissue Specificity The antibody detects endogenous levels of IKK-γ only when phosphorylated at serine 376.

Database Links

Entrez Gene 8517
Protein Accession NP_001093327.1

Application

  • Application

    Immunohistochemical analysis of paraffin-embedded human brain tissue using IKK-γ (Phospho-Ser376) antibody (left) or the same antibody preincubated with blocking peptide (right).

Application Notes
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM281801
  • Price: $336.00
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  • Lead time: 4~6 Week

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