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MINA Antibody

Catalog Number:OM284741

  • Immunohistochemistry of MINA in mouse heart tissue with MINA antibody at 5 μg/mL.

  • Western blot analysis of MINA in human heart tissue lysate with MINA antibody at (A) 1 and (B) 2 μg/mL.

  • Immunofluorescence of MINA in mouse heart tissue with MINA antibody at 20 μg/mL.

Product Profile

Product Name MINA Antibody
Antibody Type Primary Antibodies
Product description
MINA Antibody: MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.1) Tsuneoka M, Kody Y, Soejima M, et al. A novel myc target gene, mina53, that is involved in cell proliferation. J. Biol. Chem.2002; 277:35450-9.
Immunogen
MINA antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MINA. The immunogen is located within amino acids 380 - 430 of MINA.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIFIHC-PWB

IF:1:200~1:500
IHC-P:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

HumanMouse

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol MINA
Alternative Names
MINA Antibody: ROX
MDIG
NO52
MINA53
Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA
60S ribosomal protein L27a histidine hydroxylase
ROX
Sequence Similarities Predicted species reactivity based on immunogen sequence: Bovine: (80%)

Database Links

Entrez Gene 84864
Protein Accession NP_694822

Application

  • Application

    Immunohistochemistry of MINA in mouse heart tissue with MINA antibody at 5 μg/mL.

  • Application

    Western blot analysis of MINA in human heart tissue lysate with MINA antibody at (A) 1 and (B) 2 μg/mL.

  • Application

    Immunofluorescence of MINA in mouse heart tissue with MINA antibody at 20 μg/mL.

Positive Control 1) Cat. No. 1301 - Human Heart Tissue Lysate
Application Notes
IF:1:200~1:500
IHC-P:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions MINA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer MINA Antibody is supplied in PBS containing 0.02% sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM284741
  • Price: $336.00
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  • Store: Out of stock
  • Lead time: 4~6 Week
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