This gene encodes a member of the Myc superfamily of basic
helix-loop-helix leucine zipper transcriptional regulators. The
encoded protein forms a heterodimer with the cofactor MAX which
binds specific E-box DNA motifs in the promoters of target genes
and regulates their transcription. Disruption of the MAX-MXD3
complex is associated with uncontrolled cell proliferation and
tumorigenesis. Transcript variants of this gene encoding different
isoforms have been described.1) Barisone, G.A., et al. Cell Cycle 7(4):423-427(2008)
Immunogen
This MXD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human MXD3.
Max dimerization protein 3 Max dimerizer 3 Class C basic helix-loop-helix protein 13 bHLHc13 Max-associated protein 3 Max-interacting transcriptional repressor MAD3 Myx MXD3 BHLHC13 MAD3
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
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