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MYC Antibody

Catalog Number:OM285609

  • Antibody used in WB on Human Small Intestine at 0.2-1 ug/ml.

Product Profile

Product Name MYC Antibody
Antibody Type Tags Antibodies
Product description
MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.1) Frater, J.L., et al., (2006) Cancer Genet. Cytogenet. 166 (2), 139-145.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MYC.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAWB

MYC antibody can be used for detection of MYC by ELISA at 1:312500. MYC antibody can be used for detection of MYC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity

DogHumanMouseRat

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol MYC
Alternative Names
MYC
MRTL
MYCC
c-Myc
bHLHe39
Molecular Weight(MW) 49 kDa

Database Links

Entrez Gene 4609
Protein Accession NP_002458

Application

  • Application

    Antibody used in WB on Human Small Intestine at 0.2-1 ug/ml.

Positive Control 1) Cat. No. XBL-10420 - Fetal Small Intestine Tissue Lysate
Application Notes
MYC antibody can be used for detection of MYC by ELISA at 1:312500. MYC antibody can be used for detection of MYC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store MYC antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM285609
  • Price: $336.00
  • Discount Price
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  • Store: Out of stock
  • Lead time: 4~6 Week
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