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MYC Antibody

Catalog Number：OM285614

  • Immunohistochemistry staining of MYC in liver tissue using MYC monoclonal Antibody.

Product Profile

Product Name MYC Antibody
Antibody Type Tags Antibodies
Product description 
The antibody 9E10 may be used to detect the c-Myc tag. The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.
Immunogen 
Synthetic peptide sequence (AEEQKLISEEDLL) corresponding to the C-terminal region of human c-myc.

Key Feature

Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications

FACSIHCIPWB
FACS (1 - 5 ug/ml), IHC-P (10 ug/ml), IP (1 - 5 ug/ml), WB (0.5 - 2 ug/ml):
Species Reactivity

ChimpanzeeGorillaHuman
Concentration 1 mg/ml
Purification Protein G

Target Information

Gene Symbol MYC tag
Alternative Names
MYC
BHLHe39
C-Myc
MRTL
Myc proto-oncogene protein
Proto-oncogene c-Myc
Rats1
Transcription factor p64
v-myc
Tissue Specificity The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus.

Database Links

Entrez Gene 4609
Protein Accession P01106

Application

  • Application

    Immunohistochemistry staining of MYC in liver tissue using MYC monoclonal Antibody.

Application Notes
FACS (1 - 5 ug/ml), IHC-P (10 ug/ml), IP (1 - 5 ug/ml), WB (0.5 - 2 ug/ml):

Additional Information

Form Liquid
Storage Instructions Store MYC antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer PBS, 15 mM sodium azide, approx., pH 7.4.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM285614
  • Price: $396.00
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  • Lead time: 4~6 Week

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