All products Antibodies Myc Mouse Antibody

Myc Mouse Antibody

Catalog Number:OM285615

  • Western blot analysis of lysed extracts from 293 cells transfected with recombinant human Myc using Myc mouse monoclonal antibody.

Product Profile

Product Name Myc Mouse Antibody
Antibody Type Tags Antibodies
Product description
Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates1) Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.
Myc Monoclonal antibodyPeptide sequence derived from C-terminal (aa. 410-432) of human c-Myc conjugated with KLH.

Key Feature

Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications


Western Blot: 1:500~1:1000:
Species Reactivity


Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol MYC
Alternative Names
Molecular Weight(MW) 60 kDa
Tissue Specificity This mouse mAb only detects transfected proteins.

Database Links

Entrez Gene 4609
Protein Accession NP_002458.2


  • Application

    Western blot analysis of lysed extracts from 293 cells transfected with recombinant human Myc using Myc mouse monoclonal antibody.

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
Storage Instructions Store antibody at -20˚C for up to one year.
Storage Buffer Supplied in mice ascites.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM285615
  • Price: $396.00
  • Discount Price
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  • Store: Out of stock
  • Lead time: 4~6 Week
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