All products Antibodies Rabbit anti-CALR polyclonal antibody - C-terminal region

Rabbit anti-CALR polyclonal antibody - C-terminal region

Catalog Number：OM105145

Product Profile

Product Name Rabbit anti-CALR polyclonal antibody - C-terminal region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-CALR antibody: synthetic peptide directed towards the C terminal of human CALR

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

HumanMousePigRabbitRatZebra Fish
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol CALR
Gene Synonyms
RO
CRT
SSA
cC1qR
Gene Full Name Calreticulin
Gene Summary
Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Alternative Names
RO
CRT
SSA
cC1qR
Molecular Weight(MW) 48kDa
Sequence 417 amino acids

Database Links

Entrez Gene 811
SwissProt ID P27797
Protein Accession NP_004334

Application

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM105145
  • Price: $336.00
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