All products Antibodies Rabbit anti-IKBKG polyclonal antibody - N-terminal region

Rabbit anti-IKBKG polyclonal antibody - N-terminal region

Catalog Number:OM105099

  • WB Suggested Anti-IKBKG Antibody Titration: 0.2-1 ug/ml
    ELISA Titer: 1:62500
    Positive Control: Human Spleen

Product Profile

Product Name Rabbit anti-IKBKG polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen
The immunogen for anti-IKBKG antibody: synthetic peptide directed towards the N terminal of human IKBKG

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

DogGuinea PigHorseHumanMousePigRabbit

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol IKBKG
Gene Synonyms
IKBKG
Gene Full Name Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Gene Summary
IKBKG is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. IKBKG also considered to be a mediator for TAX activation of NF-kappa-B. IKBKG could be implicated in NF-kappa-B-mediated protection from cytokine toxicity.Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males (The International Incontinentia Pigmenti Consortium, 2000 [PubMed 10839543]). In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito (MIM 300337).[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2120 AF261086.1 2-2121
Alternative Names
AMCBX1
FIP-3
FIP3
Fip3p
IKK-gamma
IP
IP1
IP2
IPD2
NEMO
Molecular Weight(MW) 48kDa
Sequence 419 amino acids

Database Links

Entrez Gene 8517
SwissProt ID Q9Y6K9
Protein Accession NP_003630

Application

  • Application

    WB Suggested Anti-IKBKG Antibody Titration: 0.2-1 ug/ml
    ELISA Titer: 1:62500
    Positive Control: Human Spleen

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM105099
  • Price: $336.00
  • Discount Price
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  • Store: In stock
  • Lead time: 2~3 Week
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