All products Antibodies Rabbit anti-IRF6 polyclonal antibody - middle region

Rabbit anti-IRF6 polyclonal antibody - middle region

Catalog Number:OM105579

  • Immunohistochemistry with Placenta tissue at an antibody concentration of 5ug/ml using anti-IRF6 antibody

Product Profile

Product Name Rabbit anti-IRF6 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen
The immunogen for anti-IRF6 antibody: synthetic peptide directed towards the middle region of human IRF6

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHC

WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogHorseHumanMousePigRabbitRatSheepZebra Fish

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol IRF6
Gene Synonyms
LPS
OFC6
PIT
PPS
VWS
VWS1
Gene Full Name Interferon regulatory factor 6
Gene Summary
IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names
LPS
OFC6
PIT
PPS
VWS
VWS1
Molecular Weight(MW) 53kDa
Sequence 467 amino acids

Database Links

Entrez Gene 3664
SwissProt ID O14896
Protein Accession NP_006138

Application

  • Immunohistochemistry

    Immunohistochemistry with Placenta tissue at an antibody concentration of 5ug/ml using anti-IRF6 antibody

Application Notes
WB:1:500~1:2000
IHC:1:50~1:200
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM105579
  • Price: $336.00
  • Discount Price
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  • Store: In stock
  • Lead time: 2~3 Week
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