All products Antibodies Rabbit anti-MYC polyclonal antibody - C-terminal region

Rabbit anti-MYC polyclonal antibody - C-terminal region

Catalog Number:OM108600

Product Profile

Product Name Rabbit anti-MYC polyclonal antibody - C-terminal region
Antibody Type Tags Antibodies
Immunogen
The immunogen for anti-MYC antibody: synthetic peptide directed towards the C terminal of human MYC

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

Species Reactivity

DogHumanMouseRat

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol MYC
Gene Synonyms
c-Myc
MRTL
bHLHe39
Gene Full Name V-myc myelocytomatosis viral oncogene homolog (avian)
Gene Summary
MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Alternative Names
c-Myc
MRTL
bHLHe39
Molecular Weight(MW) 7kDa
Sequence 60 amino acids

Database Links

Entrez Gene 4609
SwissProt ID Q6LBK7
Protein Accession CAA46984

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM108600
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: In stock
  • Lead time: 2~3 Week
  • Quantity:
    - +
  • Shipping to (Please select)
Search the catalog number from any major antibody supplier/brand in the search bar above. The search engine will return OmnimAbs products for these targets.

2013 © Omnimabs , All Rights Reserved.