All products Antibodies Rabbit anti-TRAF6 polyclonal antibody - middle region

Rabbit anti-TRAF6 polyclonal antibody - middle region

Catalog Number：OM105143

  • Host: Rabbit
    Target Name: TRAF6
    Sample Tissue: Human Adult Placenta
    Antibody Dilution: 1.0ug/ml

  • Host: Rabbit
    Target Name: TRAF6
    Sample Tissue: Human Fetal Liver
    Antibody Dilution: 1.0ug/ml

  • 0.2-1 ug/ml
    ELISA Titer: 1:312500
    Positive Control: 293T cell lysate

  • Host: Rabbit
    Target Name: TRAF6
    Sample Tissue: Human Fetal Lung
    Antibody Dilution: 1.0ug/ml

Product Profile

Product Name Rabbit anti-TRAF6 polyclonal antibody - middle region
Antibody Type Primary Antibodies
Immunogen 
The immunogen for anti-TRAF6 antibody: synthetic peptide directed towards the middle region of human TRAF6

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogHorseHumanMousePigRabbitRat
Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol TRAF6
Gene Synonyms
MGC:3310
RNF85
Gene Full Name TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Gene Summary
TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein.The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported.
Alternative Names
MGC:3310
RNF85
Molecular Weight(MW) 59kDa
Sequence 522 amino acids

Database Links

Entrez Gene 7189
SwissProt ID Q9Y4K3
Protein Accession NP_004611

Application

  • Western blot

    Host: Rabbit
    Target Name: TRAF6
    Sample Tissue: Human Adult Placenta
    Antibody Dilution: 1.0ug/ml

  • Western blot

    Host: Rabbit
    Target Name: TRAF6
    Sample Tissue: Human Fetal Liver
    Antibody Dilution: 1.0ug/ml

  • Western blot

    0.2-1 ug/ml
    ELISA Titer: 1:312500
    Positive Control: 293T cell lysate

  • Western blot

    Host: Rabbit
    Target Name: TRAF6
    Sample Tissue: Human Fetal Lung
    Antibody Dilution: 1.0ug/ml

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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  • Catalog Number: OM105143
  • Price: $336.00
  • Discount Price
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  • Store: In stock
  • Lead time: 2~3 Week

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