All products Antibodies TEAD2 Antibody

TEAD2 Antibody

Catalog Number:OM293052

  • Western blot analysis in human placenta tissue lysates (35ug/lane).

  • Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Product Profile

Product Name TEAD2 Antibody
Antibody Type Primary Antibodies
Product description
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This TEAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the Central region of human TEAD2.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WB

For WB starting dilution is: 1:1000:
Species Reactivity

HumanMouse

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol TEAD2
Alternative Names
Transcriptional enhancer factor TEF-4
TEA domain family member 2
TEAD-2
TEAD2
TEF4
Molecular Weight(MW) 49 kDa

Database Links

Entrez Gene 8463
Protein Accession Q15562

Application

  • Application

    Western blot analysis in human placenta tissue lysates (35ug/lane).

  • Application

    Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Application Notes
For WB starting dilution is: 1:1000:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

  • Catalog Number: OM293052
  • Price: $336.00
  • Discount Price
  • Size:
  • Store: Out of stock
  • Lead time: 4~6 Week
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