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Catalog Number: OM259336

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OM259336-100ul

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100ul

OM259336-50ul

50ul

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Product Profile

Product Name	Importin beta-1 antibody
Antibody Type	Primary Antibodies
Product description	Mouse Monoclonal antibody to Importin beta-1The accumulation of proteins in the nucleus is mediated by short sequences of basic amino acids called nuclear localization sequences (NLSs). These sequences are necessary and sufficient to direct a protein or inert carrier to the nuclear interior. Nuclear protein import is accomplished by two sequential, energy dependent events. The first step, docking at the nuclear pore complex, requires a 54/56 kDa nuclear localization signal receptor (a-karyopherin, importin-a, SRP-a) and the nuclear transport factor p97 (NTF97, b-karyopherin, importin-b). The second step, translocation across the nuclear envelope (NE), requires the GTP-binding protein, Ran/TC4.
Immunogen	Purified NTF97 from bovine erythrocytes.
Conjugation	Agarose
Modification	Acetylated

Key Feature

Clonality	Monoclonal
Isotype	IgG2a
Clone Number	3E9
Host Species	Mouse
Tested Applications	BlockingChIPFACSICC/IFIHCInhibitionIPWB
	WB:1:500~1:1000 IP:1:100~1:500 ICC/IF:1:100~1:500 IHC:1:50~1:200
Species Reactivity	BovineDogHumanMousePigRat
Concentration	1mg/ml
Purification	Affinity purified

Target Information

Gene Synonyms	KPNB1 IMB1 IPO1 IPOB Impnb MGC2155 MGC2156 MGC2157 NTF97 karyopherin (importin) beta 1
Target	Importin beta-1

Application

Application

Application

Application

Immunofluorescent analysis of Importin beta-1 using anti-Importin beta-1 monoclonal antibody shows staining in HMVEC Cells.

Application

Immunolocalization of NTF97 in PTK cells using

Application Notes	WB:1:500~1:1000 IP:1:100~1:500 ICC/IF:1:100~1:500 IHC:1:50~1:200

Additional Information

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	PBS containing 1 mg/ml BSA and 0.05% sodium azide.

Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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