Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.| Product Name | PARP11 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PARP11, C12orf6, DKFZp779H0122, ARTD11, MIB006 |
| Product description | PARP1 encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.1) Scherer, S.E., (2006) Nature 440 (7082), 346-351. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP11. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| PARP11 antibody can be used for detection of PARP11 by ELISA at 1:312500. PARP11 antibody can be used for detection of PARP11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PARP11 |
|---|---|
| Alternative Names | PARP11 C12orf6 DKFZp779H0122 ARTD11 MIB006 |
| Molecular Weight(MW) | 39 kDa |
Application
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate |
|---|---|
| Application Notes | PARP11 antibody can be used for detection of PARP11 by ELISA at 1:312500. PARP11 antibody can be used for detection of PARP11 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store PARP11 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
Data sheet for OM287385