PON1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
The enzyme encoded by this gene is an arylesterase that
mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an
organophosphorus anticholinesterase compound that is produced in
vivo by oxidation of the insecticide parathion. Polymorphisms in
this gene are a risk factor in coronary artery disease. The gene is
found in a cluster of three related paraoxonase genes at 7q21.3.1) Ergun, M.A., et al. Biochem. Genet. (2010) In press :
Immunogen
This PON1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human PON1.
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
IHC-PWB
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50 For IHC-P starting dilution is: 1:10~50
PON1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Application Notes
For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50 For IHC-P starting dilution is: 1:10~50
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.