Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A3 contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.1) Bourdet, D.L., (2005) J. Pharmacol. Exp. Ther. 315 (3), 1288-1297.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC22A3.
Antibody used in WB on Human HepG2 at 0.5-1 ug/ml.
Application
Antibody used in IHC on Human kidney.
Positive Control
HepG2 Cell Lysate
Application Notes
WB:1:500~1:2000 IHC:1:50~1:200
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SLC22A3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.