Application
Western blot analysis of extracts from HepG2 cells using TPH2 (Phospho-Ser19) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | TPH2 (phospho Ser19) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADHD7, NTPH, TPH2 |
| Product description | This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.1) Walther D.J., Science 299:76-76(2003). |
| Immunogen | TPH2 (phospho Ser19) antibody was raised against a peptide sequence around phosphorylation site of Serine 19 (G-F-S (p)-L-D) derived from Human TPH2. |
| Modification | Phosphoralated |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TPH2 |
|---|---|
| Alternative Names | ADHD7 NTPH TPH2 |
| Molecular Weight(MW) | 56 kDa |
| Tissue Specificity | The antibody detects endogenous levels of TPH2 only when phosphorylated at serine 19. |
| Entrez Gene | 121278 |
|---|---|
| Protein Accession | NP_775489.2 |
Application
Western blot analysis of extracts from HepG2 cells using TPH2 (Phospho-Ser19) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM293825