WB
Western blot analysis using MMP2 antibody against Caco-2 (1), NIH 3T3 (2), MCF-7 (3) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using MMP2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using MMP2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human pancreatic cancer tissues using MMP2 antibody with DAB staining.| Product Name | Anti-MMP2 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MMP2 |
|---|---|
| Gene Synonyms | CLG4 MONA CLG4A MMP-2 TBE-1 MMP-II |
| Gene Full Name | matrix metallopeptidase 2 |
| Gene Summary | This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] |
| Molecular Weight(MW) | 74 kDa |
| Cellular Localization | Extracellular region or secreted;Nucleus;Membrane;Cytoplasm |
| SwissProt ID | P08253 |
|---|
WB
Western blot analysis using MMP2 antibody against Caco-2 (1), NIH 3T3 (2), MCF-7 (3) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using MMP2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using MMP2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human pancreatic cancer tissues using MMP2 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
