| Product Name | Anti-RUNX2 antibody-Biotin |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | Biotin |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISACLIAWB |
| ELISA:1:1000-1:10000 WB:1:200-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | RUNX2 |
|---|---|
| Gene Synonyms | RUNX2 CBF-alpha-1 Oncogene AML-3 OSF-2 PEA2-alpha A AML3 CBFA1 OSF2 PEBP2A |
| Gene Full Name | RUNX family transcription factor 2 |
| Gene Summary | This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016] |
| Molecular Weight(MW) | 57 kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus |
| SwissProt ID | Q13950 |
|---|
| Application Notes | ELISA:1:1000-1:10000 WB:1:200-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azi. |
