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Anti-RUNX1+RUNX2+RUNX3 antibody-poly-HRP

Catalog Number:OM641730-poly-HRP
Human;Mouse;Rat
WB;IHC
OM641730-poly-HRP
Discount Price
OM641730-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-RUNX1+RUNX2+RUNX3 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol RUNX1+RUNX2+RUNX3
Gene Synonyms CCD
AML3
CCD1
CLCD
OSF2
CBFA1
OSF-2
PEA2aA
PEBP2aA
CBF-alpha-1
Gene Full Name RUNX family transcription factor 2
Gene Summary This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
Molecular Weight(MW) 49 kDa
Source Rabbit
Cellular Localization Nucleus; Cytoplasm
Database Links
Application

WB

Western blot analysis using Anti-RUNX1+RUNX2+RUNX3 antibody against A549 (1), Caco-2 (2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using Anti-RUNX1+RUNX2+RUNX3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Anti-RUNX1+RUNX2+RUNX3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using Anti-RUNX1+RUNX2+RUNX3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Anti-RUNX1+RUNX2+RUNX3 antibody with DAB staining.

WB

Western blot analysis using RUNX1+RUNX2+RUNX3 antibody against Rat stomach(1) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azi.
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