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Anti-c-MYC antibody-poly-HRP

Catalog Number:OM641731-poly-HRP
Human;Mouse;Rat
WB;IHC
OM641731-poly-HRP
Discount Price
OM641731-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-c-MYC antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol MYC
Gene Synonyms MRTL
MYCC
c-Myc
bHLHe39
Gene Full Name MYC proto-oncogene, bHLH transcription factor
Gene Summary This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Molecular Weight(MW) 49 kDa
Source Rabbit
Cellular Localization Nucleus
Database Links
SwissProt ID P01106
Application

WB

Western blot analysis using c-MYC antibody against A431 (1), Hep G2 (2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using c-MYC antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using c-MYC antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using c-MYC antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using c-MYC antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using c-MYC antibody with DAB staining.

WB

Western blot analysis using c-MYC antibody against Mouse stomach(1),Rat stomach(2)Rat spleen(3),Rat kidney(4) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azi.
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