| Gene Symbol |
FOXO3
|
| Gene Synonyms |
FoxO3a FOXO2 AF6q21 FKHRL1 FOXO3A FKHRL1P2 |
| Gene Full Name |
forkhead box O3 |
| Gene Summary |
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) |
71 kDa(Observed:60 kDa) |
| Source |
Rabbit |
| Cellular Localization |
Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus |