| Gene Symbol |
TIMP3
|
| Gene Synonyms |
SFD
K222
K222TA2
HSMRK222 |
| Gene Full Name |
TIMP metallopeptidase inhibitor 3 |
| Gene Summary |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) |
24kDa |
| Source |
Rabbit |
| Cellular Localization |
Extracellular matrix, Secreted |
