| Gene Symbol |
MCL1
|
| Gene Synonyms |
TM EAT MCL1L MCL1S Mcl-1 BCL2L3 MCL1-ES bcl2-L-3 mcl1/EAT |
| Gene Full Name |
MCL1 apoptosis regulator, BCL2 family member |
| Gene Summary |
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010] |
| Molecular Weight(MW) |
37 kDa |
| Source |
Rabbit |
| Cellular Localization |
Membrane. Cytoplasm. Mitochondrion. Nucleus > nucleoplasm |