| Product Name | Anti-IRF3 antibody-AE |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | AE |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | CLIA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IRF3 |
|---|---|
| Gene Synonyms | C920001K05Rik IIAE7 IRF-3 |
| Gene Full Name | interferon regulatory factor 3 |
| Gene Summary | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020] |
| Alternative Names | IRF-3a IRF-3b IRF-3c IRF-3d IRF-3e IRF-3f IRF3 (phospho S386) IRF3 (pS386) IRF3 (pSer386) IRF3 phospho IRF3 phospho S386 IRF3 phospho Ser386 mIRF3a phospho IRF3 |
| Molecular Weight(MW) | 47 KDa（observed：55kDa） |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, Mitochondrion, Nucleus |
| SwissProt ID | Q14653 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
