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Anti-IRF3 antibody-HRP

Catalog Number:OM641939-HRP
Human;Mouse;Rat
WB;IHC
OM641939-HRP
Discount Price
OM641939-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-IRF3 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol IRF3
Gene Synonyms C920001K05Rik
IIAE7
IRF-3
Gene Full Name interferon regulatory factor 3
Gene Summary This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]
Alternative Names IRF-3a
IRF-3b
IRF-3c
IRF-3d
IRF-3e
IRF-3f
IRF3 (phospho S386)
IRF3 (pS386)
IRF3 (pSer386)
IRF3 phospho
IRF3 phospho S386
IRF3 phospho Ser386
mIRF3a
phospho IRF3
Molecular Weight(MW) 47 KDa(observed:55kDa)
Source Rabbit
Cellular Localization Cytoplasm, Mitochondrion, Nucleus
Database Links
SwissProt ID Q14653
Application

WB

Western blot analysis using IRF3 antibody against A431(1), COS-7(2), MCF-7(3)cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using IRF3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using IRF3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using IRF3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using IRF3 antibody with DAB staining.

WB

Western blot analysis using IRF3 antibody against Rat stomach(1) ,Rat spleen(2),Rat serum(3) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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