WB
Western blot analysis using Cyclin D3 antibody against THP-1 (1), Hep G2 (2), COS-7 (3) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Cyclin D3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Cyclin D3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using Cyclin D3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Cyclin D3 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using Cyclin D3 antibody with DAB staining.WB
Western blot analysis using Cyclin D3 antibody against Mouse brain(1) tissue.| Product Name | Anti-Cyclin D3 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CCND3 |
|---|---|
| Gene Synonyms | CCND3 |
| Gene Full Name | cyclin D3 |
| Gene Summary | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| Molecular Weight(MW) | 33 KDa |
| Source | Rabbit |
| Cellular Localization | Nucleus. Cytoplasm. Membrane. |
| SwissProt ID | P30281 |
|---|
WB
Western blot analysis using Cyclin D3 antibody against THP-1 (1), Hep G2 (2), COS-7 (3) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Cyclin D3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using Cyclin D3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using Cyclin D3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using Cyclin D3 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using Cyclin D3 antibody with DAB staining.
WB
Western blot analysis using Cyclin D3 antibody against Mouse brain(1) tissue.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
