WB
Western blot analysis using TLR7 antibody against PANC-1 (1) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using TLR7 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using TLR7 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human kidney tissues using TLR7 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using TLR7 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma2 tissues using TLR7 antibody with DAB staining.| Product Name | Anti-TLR7 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TLR7 |
|---|---|
| Gene Synonyms | IMD74 TLR7-like |
| Gene Full Name | toll like receptor 7 |
| Gene Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. The human TLR family comprises 11 members. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. For the recognition of structural components in foreign microorganisms, the various TLRs exhibit different patterns of expression as well; in this way for example, TLR-3, -7, and -8 are essential in the recognition of single-stranded RNA viruses. TLR7 senses single-stranded RNA oligonucleotides containing guanosine- and uridine-rich sequences from RNA viruses, a recognition occuring in the endosomes of plasmacytoid dendritic cells and B cells. This gene is predominantly expressed in lung, placenta, and spleen, and is phylogenetically related and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Aug 2020] |
| Molecular Weight(MW) | 121 KDa |
| Source | Rabbit |
| Cellular Localization | Endoplasmic reticulum membrane. Endosome. Lysosome. Cytoplasmic vesicle > phagosome |
| SwissProt ID | Q9NYK1 |
|---|
WB
Western blot analysis using TLR7 antibody against PANC-1 (1) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using TLR7 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using TLR7 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human kidney tissues using TLR7 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using TLR7 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma2 tissues using TLR7 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
