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Anti-OB antibody-HRP

Catalog Number:OM642010-HRP
Human;Mouse;Rat
WB;IHC
OM642010-HRP
Discount Price
OM642010-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-OB antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol LEP
Gene Synonyms Rabbit polyclonal to MMP12
OBS
LEPD
LEP
Gene Full Name leptin
Gene Summary This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017]
Molecular Weight(MW) 19 KDa
Source Rabbit
Cellular Localization Secreted.
Database Links
SwissProt ID P41159
Application

WB

Western blot analysis using OB antibody against HepG2(1) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using OB antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using OB antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using OB antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using OB antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human kidney tissues using OB antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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