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Anti-DKK1 antibody-HRP

Catalog Number:OM642015-HRP
Human;Mouse;Rat
WB;IHC
OM642015-HRP
Discount Price
OM642015-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-DKK1 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol DKK1
Gene Synonyms SK
DKK-1
Gene Full Name dickkopf WNT signaling pathway inhibitor 1
Gene Summary This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]
Molecular Weight(MW) 29 KDa
Source Rabbit
Cellular Localization Secreted
Database Links
SwissProt ID O94907
Application

WB

Western blot analysis using DKK1 antibody against HepG2 (1), A431 (2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using DKK1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human placental tissues using DKK1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using DKK1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human kidney cancer tissues using DKK1 antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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