WB
Western blot analysis using DUSP6 antibody against CaCo2 (1), HUVEC (2), HepG2 (3), MCF-7 (4) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using DUSP6 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast tissues using DUSP6 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human kidney tissues using DUSP6 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using DUSP6 antibody with DAB staining.WB
Western blot analysis using DUSP6 antibody against Mouse heart(1) tissue.| Product Name | Anti-DUSP6 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | DUSP6 |
|---|---|
| Gene Synonyms | DUS6 HH19 MKP3 PYST1 |
| Gene Full Name | dual specificity phosphatase 6 |
| Gene Summary | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014] |
| Molecular Weight(MW) | 42 kDa, 26kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm |
| SwissProt ID | Q16828 |
|---|
WB
Western blot analysis using DUSP6 antibody against CaCo2 (1), HUVEC (2), HepG2 (3), MCF-7 (4) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using DUSP6 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast tissues using DUSP6 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human kidney tissues using DUSP6 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using DUSP6 antibody with DAB staining.
WB
Western blot analysis using DUSP6 antibody against Mouse heart(1) tissue.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
