| Product Name | Anti-ALIX antibody-Gold |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | Gold |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PDCD6IP |
|---|---|
| Gene Synonyms | AIP1 ALIX DRIP4 Eig2 HP95 MCPH29 mKIAA1375 pdcd6ip RGD1561176 XELAEV_18031317mg xp95 |
| Gene Full Name | programmed cell death 6 interacting protein |
| Gene Summary | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012] |
| Alternative Names | AIP1 ALG-2 interacting protein ALG-2 interacting protein 1 ALG-2 interacting protein X ALG-2-interacting protein 1 ALG-2-interacting protein X Alg2-interacting protein 1 Alg2-interacting protein X apoptosis-linked gene 2-interacting protein X dopamine receptor interacting protein 4 E2f1-inducible protein MGC17003 PDCD6-interacting protein putative signal tranduction protein Xp95 signal transduction protein Xp95 similar to XP95 possible role in signal transduction and cell growth/death |
| Molecular Weight(MW) | 96 KDa |
| Source | Rabbit |
| Cellular Localization | Cell junction, Cytoplasm, Cytoskeleton, Secreted, Tight junction |
| SwissProt ID | Q8WUM4 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
