WB
Western blot analysis using Rb antibody against COS7 (1), A549 (2), PC-3 (3), A431 (4) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using RB antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human brain tissues using RB antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast tissues using RB antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using RB antibody with DAB staining.| Product Name | Anti-Rb antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | RB1 |
|---|---|
| Gene Synonyms | RB1 RB pRb OSRC pp110 p105-Rb PPP1R130 p110-RB1 |
| Gene Full Name | RB transcriptional corepressor 1 |
| Gene Summary | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 106 KDa |
| Source | Rabbit |
| Cellular Localization | Nucleus |
| SwissProt ID | P06400 |
|---|
WB
Western blot analysis using Rb antibody against COS7 (1), A549 (2), PC-3 (3), A431 (4) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using RB antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human brain tissues using RB antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast tissues using RB antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using RB antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
