WB
Western blot analysis using AIF antibody against A549 (1), Raji (2), HUVEC (3) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human breast tissues using AIF antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using AIF antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using AIF antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using AIF antibody with DAB staining.WB
Western blot analysis using AIF antibody agains Mouse stomach(1), Rat stomach(2),Rat spleen(3) tissue.| Product Name | Anti-AIF antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | AIFM1 |
|---|---|
| Gene Synonyms | AIFM1 AIF AUNX1 CMT2D CMTX4 COWCK DFNX5 NADMR NAMSD PDCD8 COXPD6 SEMDHL |
| Gene Full Name | apoptosis inducing factor mitochondria associated 1 |
| Gene Summary | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015] |
| Molecular Weight(MW) | 67 KDa |
| Source | Rabbit |
| Cellular Localization | Mitochondrion intermembrane space. Mitochondrion inner membrane. Cytoplasm. Nucleus. |
| SwissProt ID | O95831 |
|---|
WB
Western blot analysis using AIF antibody against A549 (1), Raji (2), HUVEC (3) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast tissues using AIF antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using AIF antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using AIF antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using AIF antibody with DAB staining.
WB
Western blot analysis using AIF antibody agains Mouse stomach(1), Rat stomach(2),Rat spleen(3) tissue.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
