WB
Western blot analysis using MAP2K2 antibody against HEK293 (1), HT1080 (2), U251 (3), HepG2 (4) and C2C12 (5) cell lysate.| Product Name | Anti-MAP2K2 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinent Proteins |
| Conjugation | poly-HRP |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:200-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MAP2K2 |
|---|---|
| Gene Synonyms | CFC4 MEK2 MKK2 MAPKK2 PRKMK2 |
| Gene Full Name | mitogen-activated protein kinase kinase 2 |
| Gene Summary | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 44 kDa |
| Source | Mouse |
| Cellular Localization | Cytoplasm, Membrane |
| SwissProt ID | P36507 |
|---|
WB
Western blot analysis using MAP2K2 antibody against HEK293 (1), HT1080 (2), U251 (3), HepG2 (4) and C2C12 (5) cell lysate.| Application Notes | WB:1:200-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
