| Gene Symbol |
RHOA
|
| Gene Synonyms |
ARHA
ARH12
RHO12
EDFAOB
RHOH12 |
| Gene Full Name |
ras homolog family member A |
| Gene Summary |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] |
| Molecular Weight(MW) |
22kDa |
| Source |
Rabbit |
| Cellular Localization |
Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane |
