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Anti-VDR antibody-poly-HRP

Catalog Number:OM642078-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642078-poly-HRP
Discount Price
OM642078-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-VDR antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol VDR
Gene Synonyms VDR
NR1I1
PPP1R163
Gene Full Name vitamin D receptor
Gene Summary This gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jun 2018]
Molecular Weight(MW) 48 kDa(Observed:68 kDa)
Source Rabbit
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID P11473
Application

WB

Western blot analysis using VDR antibody against Rb-1 (1), HepG2 (2), PANC-1 (3), A549 (4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using VDR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using VDR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast tissues using VDR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human kidney tissues using VDR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using VDR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using VDR antibody with DAB staining.

WB

Western blot analysis using VDR antibody against Rat spleen(1) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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