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Anti-TNFReceptorII antibody-poly-HRP

Catalog Number:OM642144-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642144-poly-HRP
Discount Price
OM642144-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-TNFReceptorII antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol TNFRSF1B
Gene Synonyms p75
TBPII
TNFBR
TNFR2
CD120b
TNFR1B
TNFR80
TNF-R75
p75TNFR
TNF-R-II
Gene Full Name signal transducer and activator of transcription 3
Gene Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 48 kDa
Source Rabbit
Cellular Localization Cell membrane,Secreted
Database Links
SwissProt ID P20333
Application

WB

Western blot analysis using TNFReceptorII antibody against NIH/3T3(1) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using TNFReceptorII antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using TNFReceptorII antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using TNFReceptorII antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human kidney tissues using TNFReceptorII antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using TNFReceptorII antibody with DAB staining.

WB

Western blot analysis using TNFReceptorII antibody against Mouse liver(1) ,Rat stomach(2) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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