WB
Western blot analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HTR2C antibody with DAB staining.WB
Western blot analysis using HTR2C antibody against Rat serum(1) tissue.| Product Name | Anti-HTR2C antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | HTR2C |
|---|---|
| Gene Synonyms | HTR1C 5-HT1C 5-HT2C 5HTR2C 5-HTR2C |
| Gene Full Name | 5-hydroxytryptamine receptor 2C |
| Gene Summary | This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015] |
| Molecular Weight(MW) | 52 kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P28335 |
|---|
WB
Western blot analysis using HTR2C antibody against HepG2(1),MCF-7(2), COS-7(3), A431(4) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using HTR2C antibody with DAB staining.
WB
Western blot analysis using HTR2C antibody against Rat serum(1) tissue.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
