WB
Western blot analysis using AGR2 antibody against A431(1),COS-7(2), MCF-7(3) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using AGR2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using AGR2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using AGR2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using AGR2 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using AGR2 antibody with DAB staining.WB
Western blot analysis using AGR2 antibody against Mouse heart(1) tissue.| Product Name | Anti-AGR2 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | AGR2 |
|---|---|
| Gene Synonyms | AG2 AG-2 HPC8 GOB-4 HAG-2 XAG-2 PDIA17 HEL-S-116 |
| Gene Full Name | anterior gradient 2, protein disulphide isomerase family member |
| Gene Summary | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017] |
| Molecular Weight(MW) | 20 kDa |
| Cellular Localization | Endoplasmic reticulum, Secreted |
| SwissProt ID | O95994 |
|---|
WB
Western blot analysis using AGR2 antibody against A431(1),COS-7(2), MCF-7(3) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using AGR2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human stomach cancer tissues using AGR2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using AGR2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using AGR2 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissues using AGR2 antibody with DAB staining.
WB
Western blot analysis using AGR2 antibody against Mouse heart(1) tissue.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
