| Gene Symbol |
PARK7
|
| Gene Synonyms |
DJ1
DJ-1
GATD2
HEL-S-67p |
| Gene Full Name |
Parkinsonism associated deglycase |
| Gene Summary |
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) |
20 kDa |
| Cellular Localization |
Cell membrane, Cytoplasm, Endoplasmic reticulum, Membrane, Mitochondrion, Nucleus |
