| Gene Symbol |
HK1
|
| Gene Synonyms |
HK HKD HKI HXK1 RP79 HMSNR HK1-ta HK1-tb HK1-tc NEDVIBA hexokinase |
| Gene Full Name |
hexokinase 1 |
| Gene Summary |
This gene is a member of the NGF-beta family and encodes a secreted protein Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016] |
| Cellular Localization |
Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane |