| Gene Symbol |
UBA1
|
| Gene Synonyms |
A1S9 A1ST GXP1 UBE1 A1S9T AMCX1 POC20 SMAX2 UBA1A UBE1X VEXAS CFAP124 |
| Gene Full Name |
ubiquitin like modifier activating enzyme 1 |
| Gene Summary |
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) |
118 kDa |
| Cellular Localization |
Cytoplasm, Mitochondrion, Nucleus |